Obsessive-Compulsive Disorder (OCD) is a chronic and long-lasting disorder in which a
person has uncontrollable, reoccurring thoughts (obsessions) and
behaviours (compulsions) that he or she feels the urge to repeat over
psychotherapeutic measures are the two
most widely used treatments approaches2.
Clomipramine was the first agent found to have efficacy in OCD .The drug has the pharmacological properties of the
tricyclic group of antidepressants 3.The antidepressant effects
of clomipramine are believed to be due to reuptake inhibition of serotonin and norepinephrine
while serotonin reuptake inhibition only
is believed to be accountable for the efficacy of clomipramine in the treatment
SSRIs are the first line drugs in treating OCD. The adverse effect of SSRIs
are less, so improved compliance is observed. Available SSRIs include
fluoxetine (Prozac), fluvoxamine (Luvox), paroxetine (Paxil), citalopram
(Celexa), escitalopram (Lexapro), and sertraline (Zoloft)5.
Despite the proven
efficacy of SSRIs and clomipramine in OCD,
many patients show no or just partial symptom improvement to a medication.
The combination of the antipsychotics risperidone, haloperidol, olanzapine, or
quetiapine with an SSRI was found to be to be more effective than SSRI therapy
in such cases and is suggested by the WFSBP World Federation of Societies of Biological
Prescribing a suitable
medication for a particular patient is done on the basis of many factors
including patient’s demographic characteristics, illness profile, side effects
of the medication, co morbidities. So, a study of prescription patterns
can help in identifying prevalent practices of the use of medications.7.
The concept of QOL is often considered a missing
measurement in healthcare. Inquiry into QOL proved to be useful because many
studies showed correlations between QOL and distress that often leads to
worsening of symptoms such as those of OCD.
Hence, the aim of the present study was to assess QOL in patients suffering from OCD8.
Today, in an age where health care is scrutinized, not
only for the quality of that which we provide but also the satisfaction of
those who receive it. So, it is
necessary to find out weaknesses in
systems to aid improvement through the patient’s eyes9.